Approaches for Improving the Pharmacological and Pharmacokinetics Properties of Herbal Drugs

نویسندگان

  • Manish Mathu
  • Manish Mathur
چکیده

Despite the world wide adaptability of herbal plants and their products, these conventional drugs suffering with many pharmacological and pharmacokinetics constraints. Major drawbacks related with these traditional drugs includes low aqueous solubility and physical stability, reduce absorption, rapid metabolism, instability under high acidic conditions and inability to cross blood-brain barriers. The present review article discussed various novel drug delivery approaches (like Liposome, Emulsion, Transfersome, Ethosome and Microspheres) that are using to combat with these constraints. Various important issues related with natural drugs carrier like their generalized mode of action, their advantages over conventional drugs and methods of their preparation are summarized.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

O-6: Pharmacological and Molecular Evaluation of Herbal Drugs in The Treatment of Sexual Dysfunction and As Stimulating Agents

Background: Vajikarana herbs from Ayurveda are known to enhance the sexual performance in folklore. The objective is to evaluate their effect by molecular and pharmacological screening. Materials and Methods: In the present study, the effect of four Vajikaran Rasayana herbs on penile erection, sperm count, seminal fructose content in vivo and nitric oxide (NO) release in vitro was assessed. Pen...

متن کامل

Dracocephalum kotschyi Boiss.: An iranian endemic medicinal plant; A review

Background & Aim: Iran with about 8000 plant species and 1728 endemic species; is one of the most important sources of medicinal plants. Dracocephalum kotschyi Boiss., belonging to the Lamiaceae family, is one of the endemic plants in Iran. It grows in regions of Chaharmahal and Bakhtiari, Esfahan, Gorgan, Mazandaran, Hamedan, Kermanshah, Lorestan, Tehran, Fars and the northern heights of Semna...

متن کامل

A review of pharmacological properties and functional of Cinnamon

Background & Aim: Considering the inevitable side effects of chemical drugs, nowadays, herbal medicine has gained a special importance. Cinnamon of Lauraceae Family, is commonly used as a food spice and medicine. It is famous to be, antimicrobial, anti-oxidant, anti-diabetic, anti-viral, and antispastic. It also prevents abdominal bloating, increases sweating and uterus muscle constric...

متن کامل

A review of pharmacological properties and functional of Cinnamon

Background & Aim: Considering the inevitable side effects of chemical drugs, nowadays, herbal medicine has gained a special importance. Cinnamon of Lauraceae Family, is commonly used as a food spice and medicine. It is famous to be, antimicrobial, anti-oxidant, anti-diabetic, anti-viral, and antispastic. It also prevents abdominal bloating, increases sweating and uterus muscle constric...

متن کامل

Herbal drug leaflets: are they in compliance with standards?

Leaflets inside pharmaceutical packages should include focal points about medicines being used by patients. The current study was designed to assess the compliance of information cited in herbal medicine leaflets with the standards released by the Ministry of Health and Medical Education of Iran (MHMEI). Leaflets of commonly used herbal pharmaceutical products sold in pharmacies of Iran were co...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013