Approaches for Improving the Pharmacological and Pharmacokinetics Properties of Herbal Drugs
نویسندگان
چکیده
Despite the world wide adaptability of herbal plants and their products, these conventional drugs suffering with many pharmacological and pharmacokinetics constraints. Major drawbacks related with these traditional drugs includes low aqueous solubility and physical stability, reduce absorption, rapid metabolism, instability under high acidic conditions and inability to cross blood-brain barriers. The present review article discussed various novel drug delivery approaches (like Liposome, Emulsion, Transfersome, Ethosome and Microspheres) that are using to combat with these constraints. Various important issues related with natural drugs carrier like their generalized mode of action, their advantages over conventional drugs and methods of their preparation are summarized.
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تاریخ انتشار 2013